[F4A] university creature a girl is studying sneaks out of the lab in her bag, and by the time she gets home it has made its way out and it uses its "charms" to "convince" her to she needs to breed with it.
The first transorbital lobotomy, in which a picklike instrument was forced through the back of the eye sockets to pierce the thin bone that separates the eye sockets from the frontal lobes, was performed in 1946 by Walter J Freeman II